Description

Dimethyl-5-Mehtoxycarbonyl-2-Oxopentyl Phosphonate, 98 % is a high-purity organophosphorus compound, specifically a phosphonate ester, that serves as a versatile and critical building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the precise and efficient formation of complex carbon-carbon double bonds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those containing α,β-unsaturated carbonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific alkene geometry is crucial for biological activity.
• Fine Chemical Manufacturing: Employed in the construction of specialty chemicals, flavors, fragrances, and functional materials.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process optimization.
• Peptide Mimetics & Bioactive Compounds: Facilitates the introduction of dehydroamino acid derivatives and other unsaturated structures into bioactive molecules.
• Material Science Precursor: Acts as a starting material for synthesizing phosphorus-containing polymers or ligands for catalysis.

Basic Information

Product Name	Dimethyl-5-Mehtoxycarbonyl-2-Oxopentyl Phosphonate, 98 %
CAS No.	104227-38-5
Molecular Formula	C9H17O6P
Molecular Weight	252.20 g/mol
Synonyms	Dimethyl (5-Methoxycarbonyl-2-oxopentyl)phosphonate; (5-Methoxy-5-oxo-2-oxopentyl)phosphonic Acid Dimethyl Ester; Dimethyl (5-Methoxy-5-oxo-2-oxopentyl)phosphonate; 2-Oxo-5-methoxycarbonylpentylphosphonic Acid Dimethyl Ester; HWE Reagent Derivative; Phosphonate Ester C9; CAS 104227-38-5
EINECS	Contact for details

Quality Control

Our Dimethyl-5-Mehtoxycarbonyl-2-Oxopentyl Phosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed due to potential sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.