Description

[(2R,3R,4R,5S)-5-[6-(3-Carbamoylpropylamino)Purin-9-Yl]-3,4-Dipropanoyloxy-Oxolan-2-Yl]Methyl Propanoate is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential prodrug moiety for the development of novel antiviral and anticancer therapeutics. Pharmaceutical companies, biotechnology research firms, and academic institutions engaged in nucleoside chemistry and medicinal chemistry require this specific, well-characterized material. Its precise stereochemistry and functional groups make it a valuable building block for creating targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel nucleoside analog drugs.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Investigated as a component in the design of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Prodrug Development: The propionyl ester groups make it a candidate for designing lipophilic prodrugs to enhance cellular uptake and bioavailability.

Basic Information

Product Name	[(2R,3R,4R,5S)-5-[6-(3-Carbamoylpropylamino)Purin-9-Yl]-3,4-Dipropanoyloxy-Oxolan-2-Yl]Methyl Propanoate
CAS No.	104124-23-4
Molecular Formula	C24H32N6O8
Molecular Weight	532.55 g/mol
Synonyms	9-[(2R,3R,4R,5S)-3,4-Bis(propionyloxy)-5-(propionyloxymethyl)oxolan-2-yl]-N-(3-carbamoylpropyl)-9H-purin-6-amine; 6-[(3-Carbamoylpropyl)amino]purine 2',3',5'-Tri-O-propionylriboside; 6-N-(4-Carbamoylbutyl)adenosine 2',3',5'-tripropionate; N6-(4-Carbamoylbutyl)adenosine-2',3',5'-tripropanoate; Tri-O-propionyl-N6-(4-cyanobutyl)adenosine (reduced form); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(2R,3R,4R,5S)-5-[6-(3-Carbamoylpropylamino)Purin-9-Yl]-3,4-Dipropanoyloxy-Oxolan-2-Yl]Methyl Propanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can support development projects requiring material that aligns with ICH guidelines for impurities and stability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.