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2',3'-Dideoxycytidine Monophosphate CAS NO 104086-75-1


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CAS No.:104086-75-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2',3'-Dideoxycytidine Monophosphate is a nucleotide analog monophosphate derivative, a key intermediate in the synthesis of modified nucleosides and nucleotides. This compound is of significant value in pharmaceutical research and development, particularly for its role in studying antiviral mechanisms and metabolic pathways. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of antiviral agents, prodrug synthesis, and biochemical research.

Application

  • Antiviral Research Intermediate: A crucial building block for the synthesis of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
  • Biochemical Probe: Used in enzymatic studies to investigate the activity of kinases and other nucleotide-processing enzymes.
  • Prodrug Development: Serves as a precursor in the design and synthesis of nucleotide prodrugs aimed at improving cellular uptake and therapeutic efficacy.
  • Metabolic Pathway Analysis: Employed in research to trace and understand the intracellular metabolism of nucleoside analogs.
  • Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.
  • Oligonucleotide Synthesis: Can be utilized in the preparation of modified oligonucleotides for diagnostic or research applications.

Basic Information

Product Name 2',3'-Dideoxycytidine Monophosphate
CAS No. 104086-75-1
Molecular Formula C9H14N3O6P
Molecular Weight 291.20 g/mol
Synonyms 2',3'-Dideoxycytidine 5'-monophosphate; ddCMP; 2',3'-Dideoxy-5'-CMP; 5'-Monophosphate of 2',3'-Dideoxycytidine; Cytidine, 2',3'-dideoxy-, 5'-(dihydrogen phosphate); 2',3'-ddCMP; Zalcitabine monophosphate (related analog); 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-amino-2-oxo-1,2-dihydropyrimidin-1-ium 5'-phosphate
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Quality Control

Our 2',3'-Dideoxycytidine Monophosphate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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