Description

N(6)-Adenosine is a chemically modified nucleoside derivative of adenosine, where a substituent is attached at the N6 position of the adenine base. This specific modification is of significant interest in biochemical and pharmaceutical research for its role in studying enzyme mechanisms, cellular signaling, and as a potential precursor for novel therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleotide chemistry, medicinal chemistry, and molecular biology.

Application

• Biochemical Research: Used as a reference standard, substrate, or inhibitor in enzymatic studies, particularly for adenosine deaminases, kinases, and other nucleotide-processing enzymes.
• Medicinal Chemistry & Drug Discovery: Serves as a key intermediate or building block for the synthesis of novel nucleoside analogs with potential antiviral, anticancer, or anti-inflammatory activities.
• Molecular Biology: Employed in the study of RNA modification, epigenetics, and the investigation of adenosine receptor interactions and signaling pathways.
• Diagnostic Reagent Development: Can be used in the formulation of assay kits and diagnostic reagents targeting nucleotide-related metabolic processes.
• Fine Chemical Synthesis: Acts as a specialized precursor for the custom synthesis of labeled compounds (e.g., isotopically labeled) for tracer studies and advanced research applications.

Basic Information

Product Name	N(6)-Adenosine
CAS No.	103960-10-7
Molecular Formula	C10H13N5O4
Molecular Weight	267.24 g/mol
Synonyms	6-Aminoadenosine; N6-Adenosine; Adenosine, 6-amino-; 9-β-D-Ribofuranosyladenine; 6-Amino-9-β-D-ribofuranosyl-9H-purine; N6-Adenosine; 6-Amino-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our N(6)-Adenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.