Description

N(3)-Allylthymidine is a chemically modified nucleoside derivative, specifically an allyl-substituted analog of thymidine. This compound is of significant interest in medicinal chemistry and biochemical research as a versatile building block for the synthesis of novel antiviral and anticancer agents. It serves as a crucial intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, enabling the development of targeted nucleotide-based therapies and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside analog prodrugs with potential antiviral and anticancer activities.
• Biochemical Research: Used as a modified substrate in enzymatic studies to investigate polymerase specificity and DNA replication mechanisms.
• Antiviral Drug Development: Serves as a core scaffold for creating compounds targeted against viruses such as HIV, hepatitis, and herpes.
• Probe Synthesis: Utilized in the preparation of labeled nucleotides for molecular biology and diagnostic assay development.
• Medicinal Chemistry: A valuable building block for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in nucleic acid chemistry and drug discovery.

Basic Information

Product Name	N(3)-Allylthymidine
CAS No.	103951-14-0
Molecular Formula	C13H18N2O5
Molecular Weight	282.29 g/mol
Synonyms	3-Allylthymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-3-(prop-2-en-1-yl)pyrimidine-2,4(1H,3H)-dione; Allylthymidine; Thymidine, 3-allyl-; N3-Allylthymidine
EINECS	Contact for details

Quality Control

Our N(3)-Allylthymidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.