Description

2-(4-Bromophenyl)Quinoline-4-Carbonyl Chloride is a high-purity organic intermediate characterized by its reactive acid chloride functional group and brominated aromatic system. This compound is of significant value in pharmaceutical and advanced materials research for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use as a key building block in synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with quinoline-based structures for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated phenylquinoline core.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs or conductive polymers, due to its conjugated quinoline system.
• Chemical Biology Probes: Utilized to synthesize fluorescent tags or molecular probes for biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses serving the biotechnology and fine chemical sectors.

Basic Information

Product Name	2-(4-Bromophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	103914-53-0
Molecular Formula	C16H9BrClNO
Molecular Weight	346.61 g/mol
Synonyms	4-Bromo-2-quinolinecarbonyl chloride, 2-(4-Bromophenyl)-; 2-(p-Bromophenyl)-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 2-(4-bromophenyl)-; 103914-53-0; 2-(4-Bromophenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromophenyl)Quinoline-4-Carbonyl Chloride is manufactured and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.