Description

5-Isothiocyanatoalrestatin is a specialized synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its unique molecular structure, which incorporates an isothiocyanate functional group, making it a critical precursor for the synthesis of targeted bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring precise molecular conjugation.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates and investigational new chemical entities.
• Bioconjugation Reagent: Used for labeling proteins, peptides, and other biomolecules via its reactive isothiocyanate group for diagnostic or therapeutic purposes.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the development of targeted inhibitors.
• Chemical Probe Synthesis: Integral for creating isothiocyanate-derived probes used in biochemical and cellular assays.
• API Development: Acts as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	5-Isothiocyanatoalrestatin
CAS No.	103904-10-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Alrestatin 5-isothiocyanate; 5-Isothiocyanato-alrestatin; 5-ITC-Alrestatin; [3,5-Bis(acetyloxy)phenyl][(4-formyl-3-hydroxyphenyl)methylidene]cyanamide 5-isothiocyanate derivative; (E)-2-((3,5-Diacetoxyphenyl)(cyano)methylene)-5-isothiocyanatobenzaldehyde oxime; A research-grade isothiocyanate derivative of alrestatin.
EINECS	Contact for details

Quality Control

Our 5-Isothiocyanatoalrestatin is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.