Description

5-Nitro-2,3,4,5-Tetrafluoro Benzoyl Chloride is a highly functionalized aromatic acid chloride derivative, serving as a critical building block for the synthesis of complex organic molecules. Its value lies in the strategic combination of a reactive acyl chloride group with electron-withdrawing nitro and fluorine substituents, enabling precise modifications to target structures. This compound is essential for research chemists and process development scientists in the pharmaceutical and advanced materials sectors, where it is used to introduce specific fluorinated benzoyl moieties to enhance the properties of final products.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated aromatic systems to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorinated nitrobenzoyl group can contribute to improved pesticidal activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, helping to fine-tune dielectric anisotropy, viscosity, and thermal stability.
• Polymer Modification: Employed to introduce fluorinated aromatic side chains into polymers, imparting desired characteristics such as chemical resistance, low surface energy, or specific optical properties.
• Dye & Pigment Chemistry: Intermediate for creating specialized fluorinated dyes and pigments with enhanced lightfastness, color strength, and solubility profiles.
• Cross-coupling Reagent: Functions as an electrophilic coupling partner in metal-catalyzed cross-coupling reactions for constructing complex biaryl systems.

Basic Information

Product Name	5-Nitro-2,3,4,5-Tetrafluoro Benzoyl Chloride
CAS No.	103772-10-7
Molecular Formula	C7HF4NO3Cl
Molecular Weight	255.54 g/mol
Synonyms	2,3,4,5-Tetrafluoro-5-nitrobenzoyl chloride; Benzoyl chloride, 2,3,4,5-tetrafluoro-5-nitro-; 5-Nitro-2,3,4,5-tetrafluorobenzoyl chloride; 2,3,4,5-Tetrafluoro-5-nitrobenzoic acid chloride; Tetrafluoronitrobenzoyl Chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Nitro-2,3,4,5-Tetrafluoro Benzoyl Chloride is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.