Description

1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-8-Methyl- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its reactive carbonyl chloride group makes it a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the quinoline scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides that incorporate the quinoline moiety for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags, enzyme inhibitors, and other molecular probes for biological research.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty chemicals requiring the quinoline structure.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in university and industrial laboratories.

Basic Information

Item	Details
Product Name	1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-8-Methyl- (9Ci)
CAS No.	103661-43-4
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	8-Methyl-3,4-dihydro-1(2H)-quinolinecarbonyl chloride; 8-Methyl-1,2,3,4-tetrahydroquinoline-1-carbonyl chloride; 1,2,3,4-Tetrahydro-8-methylquinoline-1-carbonyl chloride; 8-Methyl-3,4-dihydro-2H-quinoline-1-carbonyl chloride; Tetrahydro-8-methylquinoline-1-carbonyl chloride; 103661-43-4 (CAS); Quinoline-1-carbonyl chloride, 3,4-dihydro-8-methyl-
EINECS	Contact for details

Quality Control

Our 1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-8-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.