Description

1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-6-Methyl- (9Ci) is a specialized heterocyclic building block and acid chloride derivative of significant value in advanced organic synthesis. Its core value proposition lies in its reactivity as an acylating agent, enabling the efficient construction of complex amide and ester linkages within quinoline-based molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline scaffold contributes to biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts, organic semiconductors, or fluorescent dyes.
• Chemical Biology & Proteomics: Can be utilized for the derivatization of biomolecules or as a reagent for activity-based protein profiling (ABPP) due to its reactive acyl chloride group.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for fine chemical and custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-6-Methyl- (9Ci)
CAS No.	103661-41-2
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	6-Methyl-3,4-dihydro-1(2H)-quinolinecarbonyl chloride; 6-Methyl-1,2,3,4-tetrahydroquinoline-1-carbonyl chloride; 1,2,3,4-Tetrahydro-6-methylquinoline-1-carbonyl chloride; 6-Methyl-3,4-dihydro-2H-quinoline-1-carbonyl chloride; 6-Methyl-1-oxo-1,2,3,4-tetrahydroquinoline-1-carbonyl chloride; Tetrahydro-6-methylquinoline-1-carbonyl chloride; 103661-41-2 (CAS)
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-6-Methyl- (9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and undergoes rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, heat, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.