Description

3β-[(α-D-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical research and synthesis. This compound is valued for its precise stereochemistry and functional groups, which are essential for developing and studying novel therapeutic agents targeting cardiovascular functions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of cardiac drugs and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel cardioactive steroids and glycosides.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and development of potential new drug candidates for heart failure and arrhythmias.
• Analytical Standard: Employed in HPLC, LC-MS, and NMR for method development, validation, and quality control of related pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and structure-activity relationship (SAR) investigations of cardiac glycosides.

Basic Information

Product Name	3β-[(α-D-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	103368-12-3
Molecular Formula	C29H44O9
Molecular Weight	536.66 g/mol
Synonyms	14-Hydroxy-3β-(α-D-glucopyranosyloxy)-5β-card-20(22)-enolide; 3β-(α-D-Glucopyranosyloxy)-14-hydroxy-5β-card-20(22)-enolide; Cardiac Glycoside Derivative; 3β-Glucosyl-14-hydroxy-5β-card-20(22)-enolide; (3β,5β)-3-[(α-D-Glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
EINECS	Contact for details

Quality Control

Every batch of 3β-[(α-D-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to support research and cGMP-grade applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.