Description

Gdp-α-D-Mannose, Disodium Salt is a high-purity, chemically defined nucleotide sugar derivative, a critical building block in enzymatic synthesis and biochemical research. This compound serves as an activated mannose donor, enabling precise glycosylation reactions essential for producing complex carbohydrates and glycoconjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in glycobiology, drug discovery, and the development of novel therapeutic agents.

Application

• Enzymatic Glycosylation: Acts as a high-fidelity mannosyl donor for in vitro enzymatic synthesis of oligosaccharides, glycoproteins, and glycolipids.
• Glycobiology Research: A key substrate for studying glycosyltransferase enzyme kinetics, specificity, and inhibition in academic and industrial R&D.
• Biocatalyst Development: Used in the screening and engineering of novel enzymes for synthetic biology and green chemistry applications.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of carbohydrate-based vaccines, diagnostics, and investigational new drugs.
• Standards and Reagents: Employed as a certified reference material (CRM) or analytical standard for quality control in biopharmaceutical production.
• Metabolic Pathway Studies: Utilized in cell-based assays to investigate nucleotide sugar metabolism and related cellular processes.

Basic Information

Product Name	Gdp-α-D-Mannose, Disodium Salt
CAS No.	103301-73-1
Molecular Formula	C16H23N5Na2O16P2
Molecular Weight	657.29 g/mol
Synonyms	GDP-α-D-Mannose disodium salt; Guanosine 5'-(trihydrogen diphosphate) P'→5'-ester with α-D-mannose, disodium salt; α-D-Mannose 1-guanosine diphosphate disodium salt; GDP-Man disodium salt; GDP-Mannose, disodium; GMP-mannose disodium salt; Mannose-1-guanosine diphosphate disodium salt
EINECS	Contact for details

Quality Control

Our Gdp-α-D-Mannose, Disodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the stringent requirements for research and process applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg
Biological Activity	Conforms (Enzymatic Assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.