Description

5-Fluoro-2'-Deoxyuridine 5'-Monophosphate Sodium Salt is a nucleotide analog monophosphate, a critical intermediate in the synthesis of active metabolites for research and therapeutic development. This compound is valued for its role in biochemical studies, particularly in the investigation of thymidylate synthase inhibition and DNA synthesis pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for antiviral and anticancer applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex nucleotide analogs and prodrugs for antiviral and anticancer therapies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for investigating thymidylate synthase and DNA replication mechanisms.
• Antiviral Agent Development: Serves as a precursor in the research and development of nucleoside-based antiviral compounds.
• Cell Biology Studies: Employed in studies to understand cell proliferation, apoptosis, and the effects of nucleotide metabolism disruption.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Fluoro-2'-Deoxyuridine 5'-Monophosphate Sodium Salt
CAS No.	103226-10-4
Molecular Formula	C10H12FN2NaO8P
Molecular Weight	352.17 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine 5'-monophosphate sodium salt; 5-FdUMP sodium salt; 5-Fluoro-2'-deoxyuridylic acid sodium salt; FdUMP sodium; 5-Fluoro-2'-deoxyuridine 5'-(dihydrogen phosphate) monosodium salt; Sodium 5-fluoro-2'-deoxyuridine 5'-monophosphate; 5-Fluoro-2'-deoxyuridine 5'-phosphate sodium salt
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2'-Deoxyuridine 5'-Monophosphate Sodium Salt is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.