Description

Guanylyl[3'->5']Adenosine, Ammonium Salt is a high-purity biochemical reagent, specifically a dinucleoside monophosphate, essential for advanced life science research and development. This compound serves as a critical model substrate and intermediate in the study of RNA structure, enzyme kinetics, and nucleic acid metabolism. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on molecular biology and enzymology.

Application

• Enzymology Research: As a defined substrate for studying the activity, specificity, and inhibition of nucleotidyltransferases, RNA ligases, and phosphodiesterases.
• Nucleic Acid Chemistry: Serving as a key building block or intermediate in the chemical and enzymatic synthesis of oligonucleotides and RNA analogs.
• Biochemical Assay Development: Used in the formulation of high-sensitivity diagnostic assays and kits that require specific nucleotide sequences or linkages.
• Structural Biology Studies: As a reference compound for NMR, X-ray crystallography, and other analytical techniques to investigate RNA conformation and intermolecular interactions.
• Pharmaceutical Screening: Employed in target-based drug discovery programs aimed at developing novel therapeutics that modulate RNA-processing enzymes.

Basic Information

Product Name	Guanylyl[3'->5']Adenosine, Ammonium Salt
CAS No.	103213-26-9
Molecular Formula	C20H29N10O12P • xNH3
Molecular Weight	Contact for details
Synonyms	GpA ammonium salt; Guanosine(5')-P-(5')adenosine ammonium salt; 3'-5' GDPA; G(5')pp(5')A ammonium salt; Guanylyl adenosine ammonium salt; Dinucleoside monophosphate (GpA); Adenosine 5'-[P-(5'-guanosyl)]-phosphate ammonium salt
EINECS	Contact for details

Quality Control

Our Guanylyl[3'->5']Adenosine, Ammonium Salt is produced under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Ammonium Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.