Description

5'-Chloro-2'-Deoxyformycin A is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key synthetic intermediate and a valuable tool for investigating nucleoside metabolism and enzyme inhibition. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel antiviral and anticancer therapeutics. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthetic pathway of novel nucleoside-based drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to explore purine nucleoside phosphorylase (PNP) and related metabolic pathways.
• Antiviral Agent Development: Investigated for its potential activity and mechanism in the research of antiviral therapies.
• Anticancer Research: Studied for its properties in targeting specific cancer cell lines and its role in apoptosis induction.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside analogs.

Basic Information

Product Name	5'-Chloro-2'-Deoxyformycin A
CAS No.	103090-53-5
Molecular Formula	C11H12ClN5O3
Molecular Weight	297.70 g/mol
Synonyms	5'-Chloro-2'-deoxycoformycin; 5'-Chlorodeoxycoformycin; 2'-Deoxy-5'-chloroformycin A; 5'-Chloro-2'-deoxy-PNF; 9-(5-Chloro-5-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine; Cl-dCF; 5'-Chloro-2'-deoxypentostatin
EINECS	Contact for details

Quality Control

Every batch of 5'-Chloro-2'-Deoxyformycin A is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and development. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.