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2'-Deoxyuridine-5'-Triphosphate Trisodium Salt CAS NO 102814-08-4


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CAS No.:102814-08-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'-Deoxyuridine-5'-Triphosphate Trisodium Salt is a high-purity nucleotide essential for molecular biology research and diagnostic applications. This compound serves as a critical substrate for DNA polymerases and is a key component in enzymatic DNA synthesis, sequencing, and amplification techniques. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on genomics, virology, and nucleic acid biochemistry.

Application

  • DNA Sequencing & Synthesis: Acts as a natural substrate (dUTP) in enzymatic DNA synthesis and next-generation sequencing (NGS) workflows.
  • Polymerase Chain Reaction (PCR): Used in specialized PCR applications, including the detection of uracil-containing DNA.
  • Molecular Diagnostics: A key reagent in the development of diagnostic kits for viral load detection and genetic testing.
  • Biochemical Research: Employed in enzyme kinetics studies of DNA polymerases, reverse transcriptases, and other nucleic acid-processing enzymes.
  • Antiviral Drug Development: Used as a reference standard and biochemical tool in the research of antiviral compounds that target viral DNA synthesis.
  • Labeling & Detection: Serves as a precursor for the synthesis of labeled nucleotides (e.g., fluorescent or biotinylated dUTP) for probe generation and in situ hybridization.

Basic Information

Product Name 2'-Deoxyuridine-5'-Triphosphate Trisodium Salt
CAS No. 102814-08-4
Molecular Formula C9H13N2Na3O14P3
Molecular Weight 550.09 g/mol (anhydrous basis)
Synonyms dUTP trisodium salt; 2'-Deoxyuridine 5'-(tetrahydrogen triphosphate) trisodium salt; Deoxyuridine triphosphate trisodium; dUTP Na3; 5'-dUTP trisodium; Uracil deoxyribonucleoside triphosphate trisodium salt; Deoxyuridine-5'-triphosphate trisodium
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Quality Control

Our 2'-Deoxyuridine-5'-Triphosphate Trisodium Salt is manufactured under strict quality systems suitable for research and in-vitro diagnostic use. Each batch is subjected to rigorous analytical testing including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/UV) Conforms
Purity (HPLC) ≥ 95%
Assay (Enzymatic) ≥ 90%
pH (1% Solution) 7.0 - 8.5
Water Content (KF) ≤ 5.0%
Endotoxin (LAL) < 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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