Description

2'-Deoxyguanosine-5'-Diphosphate Trisodium Salt is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block and substrate in enzymatic studies, particularly those involving DNA polymerases and kinases. It is primarily utilized by researchers in molecular biology, diagnostic kit manufacturers, and companies developing antiviral or anticancer therapeutics.

Application

• Biochemical Research: Used as a substrate for DNA polymerases in PCR, DNA sequencing, and cDNA synthesis applications.
• Enzymology Studies: Essential for investigating the kinetics and mechanisms of kinases, nucleotidyltransferases, and other nucleotide-processing enzymes.
• Diagnostic Development: A key component in the formulation of reagents for molecular diagnostic assays and kits.
• Pharmaceutical R&D: Employed in screening and development programs for nucleotide analog-based drugs targeting viral infections and cancers.
• Cell Culture & Metabolism: Used in studies of cellular nucleotide metabolism and signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control in nucleotide production and research.

Basic Information

Product Name	2'-Deoxyguanosine-5'-Diphosphate Trisodium Salt
CAS No.	102783-74-4
Molecular Formula	C10H12N5Na3O10P2
Molecular Weight	529.14 g/mol (anhydrous basis)
Synonyms	dGDP Trisodium Salt; 2'-Deoxy-GDP Trisodium Salt; Deoxyguanosine Diphosphate Trisodium Salt; dGTP Trisodium Salt (common misnomer, verify structure); 5'-dGDP Na3; Guanosine, 2'-deoxy-, 5'-(trihydrogen diphosphate), trisodium salt; Deoxyguanylic acid diphosphate trisodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine-5'-Diphosphate Trisodium Salt is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if applicable)
Heavy Metals (ICP-MS)	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.