Description

A[5']P5[5']A Ammonium Salt is a specialized nucleotide analog with significant biochemical research and pharmaceutical development applications. This compound is valued for its role as a high-purity building block in oligonucleotide synthesis, enabling the creation of advanced nucleic acid-based therapeutics and diagnostic tools. It is essential for researchers and manufacturers in the fields of antisense therapy, siRNA development, and molecular diagnostics, where precise and reliable chemical intermediates are critical for success.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for the solid-phase synthesis of DNA and RNA strands.
• Therapeutic Development: Used in the research and production of antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) for targeted gene silencing therapies.
• Diagnostic Probes: Serves as a critical component in the manufacture of labeled probes for fluorescence in situ hybridization (FISH) and PCR-based assays.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
• Apoptosis Research: Utilized in studies exploring cellular signaling pathways and mechanisms of programmed cell death.
• High-Throughput Screening (HTS): Incorporated into compound libraries for drug discovery campaigns targeting nucleic acid interactions.

Basic Information

Product Name	A[5']P5[5']A Ammonium Salt
CAS No.	102783-61-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	P1,P5-Bis(5'-adenosyl) pentaphosphate ammonium salt; Diadenosine pentaphosphate ammonium salt; AP5A ammonium salt; Adenosine-5'-pentaphospho-5'-adenosine ammonium salt; 5',5'''-P1,P5-Diadenosine pentaphosphate ammonium salt; Diadenosine 5',5'''-P1,P5-pentaphosphate ammonium salt; A(5')ppppp(5')A ammonium salt
EINECS	Contact for details

Quality Control

Our A[5']P5[5']A Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the exacting standards required for life science research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.