Description

2'-Deoxyguanosine 3'-Monophosphate Ammonium Salt is a high-purity nucleotide monophosphate derivative, essential for biochemical research and pharmaceutical development. Its primary value lies in its role as a critical building block and reference standard in molecular biology, enabling precise studies of nucleic acid structure, function, and synthesis. This compound is particularly vital for researchers and manufacturers in the fields of oligonucleotide synthesis, antiviral drug development, and diagnostic assay production.

Application

• Oligonucleotide Synthesis: Serves as a protected phosphoramidite precursor or a monomer for solid-phase synthesis of DNA and RNA sequences.
• Biochemical Research: Used as a substrate, standard, or inhibitor in enzymatic studies involving polymerases, kinases, and nucleotidases.
• Pharmaceutical Intermediates: A key starting material in the synthesis of nucleotide-based antiviral and anticancer prodrugs.
• Diagnostic Reagents: Employed in the formulation of probes, primers, and components for PCR, sequencing, and other molecular diagnostic kits.
• Cell Culture & Media: Can be used as a defined nutrient component in specialized cell culture media formulations.

Basic Information

Product Name	2'-Deoxyguanosine 3'-Monophosphate Ammonium Salt
CAS No.	102783-49-3
Molecular Formula	C10H17N6O7P • xNH3
Molecular Weight	364.26 g/mol (Free acid)
Synonyms	2'-Deoxyguanosine 3'-(dihydrogen phosphate) ammonium salt; dGMP-NH4; Deoxyguanylic acid ammonium salt; 3'-dGMP ammonium salt; Guanosine, 2'-deoxy-, 3'-(dihydrogen phosphate), ammonium salt; 2'-Deoxy-3'-guanylic acid ammonium salt; dGuo-3'-P NH4+
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine 3'-Monophosphate Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Ammonium Content	Reported on COA
pH (1% Solution)	6.0 - 8.0
Endotoxin (where specified)	< 0.1 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.