Description

A[5']P6[5']A Ammonium Salt is a specialized nucleotide analog with significant utility in advanced biochemical research and development. This compound matters for its role as a critical building block and research tool in the synthesis and study of oligonucleotides. It is primarily needed by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on nucleic acid chemistry, antisense technology, and molecular biology applications.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite precursor or modified monomer in solid-phase synthesis for research-scale and therapeutic oligonucleotide production.
• Antisense & RNAi Research: Used in the development of antisense oligonucleotides (ASOs) and siRNA constructs to modulate gene expression for target validation and therapeutic discovery.
• Diagnostic Probe Development: Incorporated into nucleic acid probes for enhanced stability and specificity in diagnostic assays, including FISH and PCR-based methods.
• Apitamer Discovery: Acts as a modified nucleotide in SELEX (Systematic Evolution of Ligands by Exponential Enrichment) processes to generate nuclease-resistant aptamers.
• Bioconjugation & Labeling: Provides a reactive handle for attaching reporter molecules, such as fluorophores or quenchers, to oligonucleotides.
• Structural Biology Studies: Utilized to introduce specific modifications into RNA or DNA to study structure-function relationships and nucleic acid-protein interactions.

Basic Information

Product Name	A[5']P6[5']A Ammonium Salt
CAS No.	102783-34-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	P1,P6-Bis(5'-adenosyl) pentaphosphate ammonium salt; Diadenosine pentaphosphate ammonium salt; AP5A ammonium salt; Adenosine-5'-pentaphospho-5'-adenosine ammonium salt; P1,P6-Di(adenosine-5') pentaphosphate ammonium salt; 5',5'''-P1,P6-Diadenosine pentaphosphate ammonium salt; Bis(5'-adenosyl) pentaphosphate ammonium salt
EINECS	Contact for details

Quality Control

Our A[5']P6[5']A Ammonium Salt is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science research. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Ammonium Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.