Description

10-Isobutyryl Dithranol is a chemically modified derivative of dithranol (anthralin), designed to offer enhanced stability and handling characteristics. This compound is significant for its role as a key synthetic intermediate in the production of advanced pharmaceutical actives, particularly in dermatology. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors developing next-generation topical treatments.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel anti-psoriatic and dermatological drug candidates.
• Research & Development: Used in academic and industrial labs for studying structure-activity relationships (SAR) of anthracene derivatives.
• Fine Chemical Synthesis: Serves as a specialized intermediate in multi-step organic syntheses for high-value compounds.
• Dermatological Formulation Development: Employed in pre-formulation studies for creating more stable and less irritating topical therapies.

Basic Information

Product Name	10-Isobutyryl Dithranol
CAS No.	102768-28-5
Molecular Formula	C19H16O3
Molecular Weight	292.33 g/mol
Synonyms	1,8-Dihydroxy-10-(2-methylpropanoyl)-9(10H)-anthracenone; 10-(2-Methyl-1-oxopropyl)-1,8,9-anthracenetriol; Isobutyryl Dithranol; 10-Isobutyrylanthralin; Anthralin 10-isobutyrate derivative; 1,8,9-Anthracenetriol, 10-(2-methyl-1-oxopropyl)-; Dithranol isobutyrate
EINECS	Contact for details

Quality Control

Our 10-Isobutyryl Dithranol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.