Description

5-(2-Hydroxyethyl)Uridine is a modified nucleoside where a hydroxyethyl group is attached to the uracil base. This structural modification is significant as it can alter the biochemical properties and metabolic stability of the nucleoside, making it a valuable intermediate in advanced research and synthesis. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in nucleoside chemistry, prodrug development, and as a building block for oligonucleotide synthesis.

Application

• Key intermediate in the synthesis of modified oligonucleotides and antisense agents.
• Building block for prodrug development to enhance drug delivery and bioavailability.
• Substrate for enzymatic studies and research into nucleoside metabolism.
• Precursor in the development of novel therapeutic nucleoside analogs.
• Research chemical for studying RNA structure, function, and modification.
• Starting material for labeling studies and tracer synthesis in biochemical research.

Basic Information

Product Name	5-(2-Hydroxyethyl)Uridine
CAS No.	102691-28-1
Molecular Formula	C11H16N2O7
Molecular Weight	288.25 g/mol
Synonyms	5-(2-Hydroxyethyl)uridine; Uridine, 5-(2-hydroxyethyl)-; 2'-Deoxy-5-(2-hydroxyethyl)uridine (common misnomer); 5-HEU; 5-(β-Hydroxyethyl)uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(2-hydroxyethyl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-(2-Hydroxyethyl)Uridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.