Description

3-Fluoro-4-Methylphenyl Isothiocyanate is a versatile aromatic isothiocyanate derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive isothiocyanate (-N=C=S) group, which readily undergoes addition and cyclization reactions to form heterocyclic cores. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiourea derivatives and heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by incorporating the fluorinated phenyl moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of monomers or functional agents for advanced polymers and specialty materials.
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules due to the electrophilic isothiocyanate group.

Basic Information

Product Name	3-Fluoro-4-Methylphenyl Isothiocyanate
CAS No.	102561-42-2
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	4-Methyl-3-fluorophenyl isothiocyanate; 3-Fluoro-p-tolyl isothiocyanate; 1-Fluoro-2-isothiocyanato-4-methylbenzene; (3-Fluoro-4-methylphenyl)isothiocyanate; Isothiocyanic acid, 3-fluoro-4-methylphenyl ester; 3-Fluoro-4-methylbenzenisothiocyanate
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Methylphenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.