Description

3,7,12-Trihydroxy-7-Methylcholanoic Acid is a methylated derivative of a trihydroxycholanoic acid, a key intermediate in the synthesis of bile acids and related steroidal compounds. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of metabolic pathways and liver function. It serves the needs of advanced research laboratories, pharmaceutical manufacturers, and fine chemical synthesis specialists developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel bile acid analogs and steroidal pharmaceuticals.
• Metabolic Research: Used as a reference standard or probe in studies of cholesterol metabolism, liver function, and bile acid biosynthesis pathways.
• Biochemical Reagent: Employed in enzymatic assays and as a substrate for studying hydroxysteroid dehydrogenases and related enzymes.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the preparation of complex, high-value steroidal compounds.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in organic chemistry and biochemistry.

Basic Information

Product Name	3,7,12-Trihydroxy-7-Methylcholanoic Acid
CAS No.	102362-49-2
Molecular Formula	C25H42O5
Molecular Weight	422.60 g/mol
Synonyms	7-Methyl-3,7,12-trihydroxycholanoic acid; 7α-Methyl-3α,7α,12α-trihydroxy-5β-cholan-24-oic acid; 7-Methylchenodeoxycholic acid derivative; 3,7,12-Trihydroxy-7-methyl-5β-cholan-24-oic acid; 7-Methyl-3,7,12-trihydroxy-5β-cholanic acid; 7-Methyl-trihydroxy bile acid
EINECS	Contact for details

Quality Control

Our 3,7,12-Trihydroxy-7-Methylcholanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.