Description

Adenosine 5'-Succinate is a chemically modified nucleotide derivative where a succinyl group is esterified to the 5'-hydroxyl of adenosine. This modification is crucial for creating prodrugs and enhancing the delivery and bioavailability of adenosine in various therapeutic and research contexts. It serves as a key biochemical building block and intermediate for pharmaceutical development, particularly in cardiology, neurology, and metabolic research. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of adenosine prodrugs and novel therapeutic agents targeting cardiovascular and neurological disorders.
• Biochemical Research: Used as a substrate or precursor in enzymatic studies, metabolic pathway analysis, and signal transduction research involving adenosine receptors.
• Prodrug Synthesis: The succinate moiety facilitates the development of prodrugs with improved membrane permeability and targeted release profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Nucleotide Chemistry: A valuable building block for the chemical modification of nucleotides and the creation of labeled analogs for diagnostic applications.
• Cosmeceutical Formulations: Investigated for use in advanced skincare products for its potential anti-inflammatory and cellular energy-boosting properties.

Basic Information

Product Name	Adenosine 5'-Succinate
CAS No.	102029-71-0
Molecular Formula	C14H17N5O8
Molecular Weight	383.32 g/mol
Synonyms	5'-O-Succinyladenosine; Adenosine 5'-monosuccinate; N6-(Adenin-9-yl)-5'-O-(3-carboxy-1-oxopropoxy)-5'-deoxy-β-D-ribofuranose; Succinyl Adenosine Ester; 9-β-D-Ribofuranosyladenine 5'-(hydrogen succinate); Adenosine, 5'-(hydrogen succinate); 5'-Adenylic acid, succinyl ester
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Succinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP-grade requirements. Specifications are designed to meet the high standards of pharmaceutical and biotechnology applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.