Description

3-Pyridinecarbonyl Chloride, 6-(Methylthio)- (9Ci) is a specialized heterocyclic building block and key synthetic intermediate. Its value lies in its reactive acid chloride functional group, which enables efficient coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the pyridine-thioether motif.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials due to its aromatic and modifiable structure.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and enzyme interactions.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 6-(Methylthio)- (9Ci)
CAS No.	101990-64-1
Molecular Formula	C7H6ClNOS
Molecular Weight	187.64 g/mol
Synonyms	6-(Methylthio)nicotinoyl chloride; 6-(Methylsulfanyl)nicotinoyl chloride; 6-(Methylthio)pyridine-3-carbonyl chloride; 3-Carbonyl chloride-6-(methylthio)pyridine; 6-Methylthiopyridine-3-carboxylic acid chloride; 6-Methylsulfanyl-nicotinoyl chloride; 6-Methylmercaptonicotinoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 6-(Methylthio)- (9Ci) is manufactured and tested under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.