Description

Butenafine Hydrochloride is a synthetic benzylamine antifungal agent widely recognized for its potent and broad-spectrum activity. It is a critical active pharmaceutical ingredient (API) essential for the formulation of topical antifungal treatments. This compound is primarily utilized by pharmaceutical manufacturers and research institutions in the development of creams, gels, and powders for treating dermatological infections.

Application

• Pharmaceutical API: Primary active ingredient in prescription and over-the-counter (OTC) topical antifungal medications.
• Dermatological Creams & Gels: Formulated for the treatment of tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch).
• Antifungal Powders & Sprays: Used in formulations designed for drying and treating fungal infections on the skin.
• Veterinary Pharmaceuticals: Incorporated into topical treatments for fungal skin conditions in animals.
• Research & Development: Serves as a reference standard and key intermediate in biochemical research for novel antifungal agents.
• Cosmeceutical Applications: Potential use in specialized foot care and hygiene products targeting fungal prevention.

Basic Information

Product Name	Butenafine Hydrochloride
CAS No.	101827-46-7
Molecular Formula	C23H27N • HCl
Molecular Weight	353.93 g/mol
Synonyms	Butenafine HCl; (E)-N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine Hydrochloride; (±)-Butenafine Hydrochloride; Mentax (Brand Name); KP-363 Hydrochloride; N-[(4-tert-Butylphenyl)methyl]-N-methyl-1-naphthalenemethylamine Hydrochloride; 1-Naphthalenemethanamine, N-[(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride, (E)-
EINECS	Contact for details

Quality Control

Our Butenafine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from tests such as Identification, Assay, and related substances analysis. Our quality commitment aligns with cGMP principles to ensure supply reliability and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.