Description

2'-Deoxy-4-Desmethylwyosine is a modified nucleoside derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial intermediate and reference standard in the synthesis and study of more complex nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, nucleic acid chemistry, and the development of novel therapeutic agents. Its precise structure makes it a valuable tool for probing biological mechanisms and for quality control in the production of related active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathway for novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and probe in studies of tRNA modification, enzyme mechanisms, and nucleic acid metabolism.
• Antiviral Drug Discovery: Serves as a core scaffold for the development of new therapeutic agents targeting viral polymerases.
• Academic Research: Employed in universities and research institutes for fundamental studies in organic chemistry and medicinal chemistry.
• Quality Control & Analytical Standards: Used as a high-purity certified reference material (CRM) for HPLC, LC-MS, and NMR analysis in API manufacturing.
• Process Development: Acts as a critical starting material or intermediate in scaling up the production of specialized nucleosides.

Basic Information

Product Name	2'-Deoxy-4-Desmethylwyosine
CAS No.	101803-00-3
Molecular Formula	C14H17N5O4
Molecular Weight	319.32 g/mol
Synonyms	4-Desmethylwyosine; 2'-Deoxy-4-demethylwyosine; 1H-Imidazo[1,2-a]purin-7(3H)-one, 3-β-D-deoxyribofuranosyl-2,3-dihydro-; 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3,4-dihydro-2,4-dioxo-1H-imidazo[1,2-a]purine; Wyosine derivative; Nucleoside analog Y; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-4-Desmethylwyosine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.