Description

1-Chloro-4-Isothiocyanato-Naphthalene is a versatile naphthalene-based organic intermediate featuring both chloro and isothiocyanate functional groups. This bifunctional structure makes it a valuable building block for synthesizing more complex molecules, particularly in the development of specialized dyes, pigments, and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and industrial manufacturers in the fine chemical, agrochemical, and pharmaceutical sectors for advanced synthesis and product development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), leveraging its reactive sites for molecular diversification.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the naphthalene core contributes to biological activity.
• Dye and Pigment Manufacturing: Acts as a crucial intermediate for creating high-performance, color-fast dyes and organic pigments for industrial applications.
• Liquid Crystal and OLED Material Research: Employed in the development of organic electronic materials due to the planar naphthalene structure and modifiable functional groups.
• Chemical Biology & Proteomics: Utilized as a reactive probe or linker in bioconjugation and protein labeling studies, taking advantage of the isothiocyanate group's affinity for amines.
• Polymer Modification: Functions as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	1-Chloro-4-Isothiocyanato-Naphthalene
CAS No.	101670-65-9
Molecular Formula	C11H6ClNS
Molecular Weight	219.69 g/mol
Synonyms	4-Chloro-1-naphthyl isothiocyanate; 1-Chloro-4-isothiocyanatonaphthalene; 1-Naphthalenol, 4-chloro-, isothiocyanate; 4-Chloro-1-naphthalene isothiocyanate; Naphthalene, 1-chloro-4-isothiocyanato-; Isothiocyanic acid, 4-chloro-1-naphthyl ester
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-4-Isothiocyanato-Naphthalene is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthesis. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.