Description

3-Chloro-2,4,5-Trifluorobenzoyl Chloride is a highly reactive and versatile fluorinated aromatic acid chloride intermediate. Its value lies in its ability to introduce the 3-chloro-2,4,5-trifluorobenzoyl moiety into complex molecules, a key structural motif in advanced synthesis. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for constructing active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a key precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering material properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: A valuable reagent in academic and industrial laboratories for Friedel-Crafts acylation and other coupling reactions to create complex aromatic systems.
• Advanced Material Research: Used in the development of novel organic electronic materials and dyes.

Basic Information

Product Name	3-Chloro-2,4,5-Trifluorobenzoyl Chloride
CAS No.	101513-78-4
Molecular Formula	C7HCl2F3O
Molecular Weight	228.98 g/mol
Synonyms	2,4,5-Trifluoro-3-chlorobenzoyl chloride; 3-Chloro-2,4,5-trifluorobenzoic acid chloride; Benzoyl chloride, 3-chloro-2,4,5-trifluoro-; 3-Chloro-2,4,5-trifluorobenzoic acid chloride; 2,4,5-Trifluoro-3-chlorobenzoic acid chloride; 3-Chloro-2,4,5-trifluorobenzoylchloride; 3-Chloro-2,4,5-trifluoro-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4,5-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong bases, alcohols, and amines. Due to its hygroscopic and highly volatile nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.