Description

8-Aminoguanosine Triphosphate is a chemically modified nucleotide triphosphate analog that serves as a critical building block for advanced biochemical research and development. Its unique structure, featuring an amino group at the 8-position of the guanine base, makes it a valuable tool for probing enzyme mechanisms and developing novel molecular probes. This compound is primarily utilized by researchers and manufacturers in the fields of molecular biology, enzymology, and diagnostic assay development. Its high purity and reliable performance are essential for sensitive applications requiring precise biochemical activity.

Application

• Enzymology Studies: Used as a substrate or inhibitor to study the kinetics and mechanisms of ATP/GTP-binding enzymes, polymerases, and kinases.
• Molecular Probe Synthesis: Acts as a key precursor for the enzymatic or chemical synthesis of labeled nucleotides for detection and imaging.
• Diagnostic Assay Development: Incorporated into the development of sensitive assays for detecting specific enzymatic activities or for high-throughput screening (HTS).
• Nucleic Acid Research: Employed in studies investigating nucleic acid structure, function, and protein-nucleic acid interactions.
• Bioconjugation & Labeling: The reactive amino group facilitates site-specific conjugation to fluorophores, biotin, or other reporter molecules.
• Pharmaceutical Research: Investigated for potential applications in drug discovery targeting nucleotide metabolic pathways.

Basic Information

Product Name	8-Aminoguanosine Triphosphate
CAS No.	101212-50-4
Molecular Formula	C10H17N6O13P3
Molecular Weight	558.18 g/mol
Synonyms	8-Amino-GTP; 8-NH2-GTP; Guanosine-5'-triphosphate, 8-amino-; 8-Aminoguanosine 5'-triphosphate; 8-Amino-GTP trisodium salt; 8-Amino-guanosine-5'-triphosphate; ATP analog (8-amino-GTP)
EINECS	Contact for details

Quality Control

Every batch of 8-Aminoguanosine Triphosphate is manufactured and tested under stringent quality management protocols to ensure the highest standards of purity and consistency required for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic analyses, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water or suitable aqueous buffer
Biological Activity	Tested in applicable enzyme system

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.