Description

Oxo-(2-Phenyl-Indolizin-3-Yl)-Acetyl Chloride is a specialized high-purity chemical building block, an acid chloride derivative of a phenyl-indolizine scaffold. This compound is critical for the synthesis of complex heterocyclic molecules, offering a reactive handle for amide bond formation and further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs) and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Organic Synthesis: Serves as a versatile precursor for creating complex indolizine-based libraries and fine chemicals.
• Agrochemical Development: Intermediate in the research and synthesis of new generation pesticides and herbicides.
• Material Science: Potential monomer or precursor for advanced polymers and organic electronic materials.

Basic Information

Product Name	Oxo-(2-Phenyl-Indolizin-3-Yl)-Acetyl Chloride
CAS No.	101081-39-4
Molecular Formula	C16H10ClNO2
Molecular Weight	283.71 g/mol
Synonyms	2-Phenylindolizine-3-carbonyl chloride; 3-(Chloroformyl)-2-phenylindolizine-1-carboxaldehyde; 2-Phenyl-1H-indolizine-3-carbonyl chloride; (2-Phenyl-1H-indolizin-3-yl)(oxo)acetyl chloride; 2-Phenylindolizine-3-glyoxyloyl chloride; α-Oxo-2-phenyl-1H-indolizine-3-acetyl chloride
EINECS	Contact for details

Quality Control

Every batch of Oxo-(2-Phenyl-Indolizin-3-Yl)-Acetyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.