Description

Hellebrigeninmonoacetat is a specialized cardiac glycoside derivative, a high-purity reference standard and key intermediate for advanced pharmaceutical research and development. This compound is valued for its precise chemical structure, which is critical for studying cardiac activity and synthesizing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on cardiovascular drug discovery and biochemical analysis.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, purity testing, and quantification of related compounds in analytical methods like HPLC and LC-MS.
• Biochemical Research: Serves as a crucial tool in pharmacological studies to investigate the mechanisms of action of cardiac glycosides on sodium-potassium ATPase.
• Active Pharmaceutical Ingredient (API) Intermediate: A key building block in the multi-step synthesis of potential novel cardiac drugs and other specialized therapeutic agents.
• Academic Research: Employed in university and institutional labs for studying natural product chemistry, structure-activity relationships (SAR), and metabolic pathways.
• Quality Control Laboratories: Essential for developing and validating in-house testing protocols for raw materials and finished products containing related glycosides.

Basic Information

Product Name	Hellebrigeninmonoacetat
CAS No.	100991-83-1
Molecular Formula	C27H36O8
Molecular Weight	488.57 g/mol
Synonyms	Hellebrigenin 3-acetate; 3β-Acetoxy-5β,14β-dihydroxy-19-oxo-bufa-20,22-dienolide; 3β-Acetoxy-14-hydroxy-19-oxobufa-20,22-dienolide; Hellebrigenin acetate; 3-Acetylhellebrigenin; (3β,5β)-3-(Acetyloxy)-14,19-dihydroxybufa-20,22-dienolide; 19-Oxobufalin 3-acetate
EINECS	Contact for details

Quality Control

Our Hellebrigeninmonoacetat is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.