Description

2-Thiopheneacetyl Chloride, 3-Methoxy-α-Oxo- (9Ci) is a specialized organic building block featuring a reactive acid chloride group on a substituted thiophene scaffold. This compound matters as a critical intermediate for synthesizing complex molecules, enabling the efficient introduction of the 3-methoxy-α-oxo-2-thiopheneacetyl moiety into target structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene ring's bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of conductive polymers and advanced organic electronic materials.
• Chemical Synthesis Reagent: Employed in organic synthesis for peptide coupling reactions and the preparation of amides, esters, and ketones from carboxylic acids.
• Ligand and Catalyst Development: Useful for constructing complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 3-Methoxy-α-Oxo- (9Ci)
CAS No.	100751-57-3
Molecular Formula	C7H5ClO2S
Molecular Weight	188.63 g/mol
Synonyms	3-Methoxy-2-thiopheneglyoxyl chloride; 2-(3-Methoxythiophen-2-yl)-2-oxoacetyl chloride; 3-Methoxy-2-thiopheneglyoxylic acid chloride; 3-Methoxythiophene-2-glyoxyloyl chloride; α-Oxo-3-methoxy-2-thiopheneacetyl chloride; 2-(3-Methoxythiophene-2-carbonyl)formyl chloride; (3-Methoxythiophen-2-yl)(oxo)acetyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Thiopheneacetyl Chloride, 3-Methoxy-α-Oxo- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.