Description

2-Thiopheneacetyl Chloride, 5-(Cyanomethyl)-α-Oxo- (9Ci) is a high-purity, specialized organic intermediate featuring a reactive acid chloride group and a nitrile functionality on a thiophene scaffold. This compound matters for its role as a critical building block in the synthesis of complex molecules, enabling the introduction of key structural motifs. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and conductive materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital component for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 5-(Cyanomethyl)-α-Oxo- (9Ci)
CAS No.	100750-92-3
Molecular Formula	C8H4ClNO2S
Molecular Weight	213.64 g/mol
Synonyms	5-(Cyanomethyl)-2-thiopheneacetyl chloride, α-oxo-; 5-(Cyanomethyl)-2-thiopheneglyoxyl chloride; 2-Thiopheneacetyl chloride, 5-(cyanomethyl)-α-oxo-; 5-(Cyanomethyl)thiophene-2-glyoxylic acid chloride; 2-(5-Cyanomethylthiophen-2-yl)-2-oxoacetyl chloride; (5-Cyanomethylthiophen-2-yl)(oxo)acetyl chloride; 2-Oxo-2-(5-(cyanomethyl)thiophen-2-yl)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride, 5-(Cyanomethyl)-α-Oxo- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.