Description

2-Thiopheneacetyl Chloride, 5-Ethoxy-α-Oxo- (9Ci) is a specialized heterocyclic building block and acid chloride derivative. This compound is valued for its high reactivity, serving as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel thiophene-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation, labeling biomolecules, or synthesizing activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: Essential for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 5-Ethoxy-α-Oxo- (9Ci)
CAS No.	100750-87-6
Molecular Formula	C9H9ClO3S
Molecular Weight	232.68 g/mol
Synonyms	5-Ethoxy-2-thiopheneglyoxylic acid chloride; 2-(5-Ethoxy-2-thienyl)-2-oxoacetyl chloride; 5-Ethoxy-2-thiopheneacetyl chloride, α-oxo-; 2-Thiopheneacetyl chloride, 5-ethoxy-α-oxo-; 5-Ethoxythiophene-2-glyoxyloyl chloride; α-Oxo-5-ethoxy-2-thiopheneacetyl chloride; (5-Ethoxy-2-thienyl)(oxo)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride, 5-Ethoxy-α-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to amber liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.