Description

Cyclopropanecarbonyl Chloride, 2-(1,3-Butadienyl)-, [1Alpha,2Alpha(E)]- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group attached to a cyclopropane ring conjugated with a butadiene moiety. This unique structure makes it a valuable building block for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound is supplied with a CAS number of 100515-96-6.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex cyclic architectures.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection, leveraging its cyclopropane unit which is a common motif in modern pesticides.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Employed to create labeled compounds or activity-based probes for studying enzyme function and biological pathways.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel chiral ligands or organometallic catalysts used in asymmetric synthesis.
• Fine Chemical Production: Intermediate for the manufacture of complex fragrance or flavor molecules where the strained ring system contributes unique olfactory characteristics.

Basic Information

Item	Details
Product Name	Cyclopropanecarbonyl Chloride, 2-(1,3-Butadienyl)-, [1Alpha,2Alpha(E)]- (9Ci)
CAS No.	100515-96-6
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	(1R,2R)-2-[(1E)-1,3-Butadien-1-yl]cyclopropanecarbonyl chloride; (1R,2R)-2-[(E)-Buta-1,3-dien-1-yl]cyclopropane-1-carbonyl chloride; trans-2-[(E)-1,3-Butadien-1-yl]cyclopropanecarbonyl chloride; [1α,2α(E)]-2-(1,3-Butadienyl)cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2-(1,3-Butadienyl)-, [1Alpha,2Alpha(E)]- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isomeric Purity (GC/HPLC)	≥ 98.0% [1Alpha,2Alpha(E)]-
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.