Description

1-Pyrrolidineacetyl Chloride, α-Oxo- (9Ci) is a versatile and highly reactive organic acid chloride building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors to introduce key functional groups. Its reactivity makes it a valuable intermediate for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrolidine or amide motifs.
• Peptide Mimetics & Drug Discovery: Used in medicinal chemistry to create peptide analogs and novel small molecule libraries for biological screening.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of specialty polymers, ligands for catalysis, and functional organic materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in biochemical research and diagnostic development.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	1-Pyrrolidineacetyl Chloride, α-Oxo- (9Ci)
CAS No.	100481-08-1
Molecular Formula	C6H8ClNO2
Molecular Weight	161.59 g/mol
Synonyms	2-Oxo-2-(pyrrolidin-1-yl)acetyl chloride; 1-Pyrrolidineglyoxyloyl chloride; 2-(1-Pyrrolidinyl)-2-oxoacetyl chloride; Pyrrolidine-1-carbonyl chloride, oxo-; NSC 405124; α-Oxo-1-pyrrolidineacetyl chloride; Pyrrolidin-1-yl(oxo)acetyl chloride
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidineacetyl Chloride, α-Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles for production, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.