Description

[22R,(+)]-15α-Acetyloxy-5,6β-Epoxy-4β,14β,22-Trihydroxy-1-Oxo-5β-Ergosta-2,24-Diene-26-Oic Acid 26,22-Lactone is a complex, high-purity ergostane-type steroidal lactone, identified by CAS No. 100217-92-3. This compound is of significant interest for its role as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis and study of novel bioactive steroidal compounds, particularly those exploring anti-inflammatory or metabolic pathways.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating sterol biosynthesis, enzyme inhibition, and receptor binding assays.
• Reference Material: Serves as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Academic Research: Employed in universities and research institutes for exploring the structure-activity relationships (SAR) of complex natural products.

Basic Information

Product Name	[22R,(+)]-15α-Acetyloxy-5,6β-Epoxy-4β,14β,22-Trihydroxy-1-Oxo-5β-Ergosta-2,24-Diene-26-Oic Acid 26,22-Lactone
CAS No.	100217-92-3
Molecular Formula	C30H40O9
Molecular Weight	544.64 g/mol
Synonyms	(22R)-15α-Acetoxy-5,6β-epoxy-4β,14β,22-trihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid 26,22-lactone; 15α-Acetyloxy-5,6β-epoxy-4β,14β,22-trihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid δ-lactone; 5,6β-Epoxy-4β,14β,15α,22-tetrahydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic acid 26,22-lactone 15-acetate; Ergostane Steroid Lactone Derivative; 100217-92-3
EINECS	Contact for details

Quality Control

Our [22R,(+)]-15α-Acetyloxy-5,6β-Epoxy-4β,14β,22-Trihydroxy-1-Oxo-5β-Ergosta-2,24-Diene-26-Oic Acid 26,22-Lactone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.