Description

4-[(4-Isothiocyanatophenyl)Sulfonyl]Morpholine is a specialized organic building block featuring a reactive isothiocyanate group linked to a sulfonyl-morpholine moiety. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and bioactive molecules, where it facilitates the introduction of the thiourea pharmacophore. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel sulfonamide derivatives and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly those targeting enzymes via sulfonamide and thiourea linkages.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and plant growth regulators that require specific sulfonyl-based active ingredients.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent in the production of specialty polymers, coatings, and resins with tailored properties.
• Bioconjugation & Probe Synthesis: The reactive isothiocyanate group enables labeling and conjugation of biomolecules (proteins, antibodies) for diagnostic and research applications.
• Chemical Biology Tool: Utilized in activity-based protein profiling (ABPP) and the development of covalent inhibitors for target identification and validation studies.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and sulfonamide libraries.

Basic Information

Product Name	4-[(4-Isothiocyanatophenyl)Sulfonyl]Morpholine
CAS No.	100060-98-8
Molecular Formula	C11H12N2O3S2
Molecular Weight	284.35 g/mol
Synonyms	4-(4-Isothiocyanatobenzenesulfonyl)morpholine; 4-Morpholinesulfonylphenyl isothiocyanate; N-(4-Isothiocyanatophenylsulfonyl)morpholine; 4-Isothiocyanatophenyl morpholine-4-sulfonate; Benzenesulfonamide, 4-isothiocyanato-N-morpholino-; 100060-98-8; 4-(4-Isothiocyanato-phenylsulfonyl)-morpholine
EINECS	Contact for details

Quality Control

Our 4-[(4-Isothiocyanatophenyl)Sulfonyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Melting Point	Contact for details
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.