Description

5-Chloro-6β,22,27-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is a complex, highly functionalized ergostane derivative that serves as a critical advanced intermediate in the synthesis of novel bioactive compounds. Its unique steroidal framework, featuring multiple oxygenated functional groups and a chlorine substituent, makes it a valuable scaffold for pharmaceutical research and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new therapeutic agents, particularly in areas such as oncology, endocrinology, and anti-infective research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and investigational new chemical entities (NCEs).
• Biochemical Research: Used as a reference standard or precursor in studies of sterol biosynthesis and metabolic pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for the development of new synthetic methodologies targeting complex natural product analogs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	5-Chloro-6β,22,27-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone
CAS No.	19898-96-5
Molecular Formula	C28H37ClO6
Molecular Weight	505.05 g/mol
Synonyms	5-Chloro-6β,22,27-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone; 5α-Ergosta-2,24-dien-26-oic acid, 5-chloro-6β,22,27-trihydroxy-1-oxo-, δ-lactone; 5-Chloro-6β,22,27-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone; 5-Chloro-6β,22,27-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid lactone; Ergostane derivative, 5-chloro-6β,22,27-trihydroxy-1-oxo-δ-lactone.
EINECS	Contact for details

Quality Control

Our 5-Chloro-6β,22,27-Trihydroxy-1-Oxo-5α-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment to maintain stability and purity. For long-term storage, consider desiccants and inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.