Description

12 α-Hydroxyprogesterone is a key steroid intermediate of significant importance in pharmaceutical synthesis. This compound is valued for its role as a versatile building block in the production of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and life sciences industries for the development of therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of various steroid hormones and related therapeutic compounds.
• Research & Development: Used in laboratory settings for metabolic studies, biochemical research, and the development of new synthetic pathways for steroid derivatives.
• API Synthesis: Serves as a building block in the manufacture of specific corticosteroid or progestogen active pharmaceutical ingredients under controlled GMP conditions.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	12 α-Hydroxyprogesterone
CAS No.	19897-02-0
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	12α-Hydroxyprogesterone; 12α-Hydroxy-4-pregnene-3,20-dione; 12α-Hydroxypregn-4-ene-3,20-dione; 12α-OH-P4; 12α-Hydroxyprogestone; 12α-Hydroxypregnenedione
EINECS	Contact for details

Quality Control

Our 12 α-Hydroxyprogesterone is produced and tested to meet the stringent requirements of pharmaceutical-grade intermediates. Quality is assured through a comprehensive battery of analytical tests including HPLC for purity, IR for identification, and specific tests for related substances. A Certificate of Analysis (COA) documenting all specifications is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.