Description

(20R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One CAS NO 19865-90-8 is a high-purity, semi-synthetic dammarane-type triterpenoid derivative. This compound is valued for its role as a critical intermediate in the synthesis of bioactive ginsenosides and other pharmacologically active natural products. It is essential for research and development laboratories in the pharmaceutical, nutraceutical, and fine chemical industries seeking to develop novel therapeutic agents or reference standards.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the production of ginsenosides and other triterpenoid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in herbal extract and pharmaceutical analysis.
• Nutraceutical Research: Serves as a starting material for the development of high-value, standardized botanical extracts and dietary supplements.
• Academic & R&D: Utilized in university and institutional research for studying the structure-activity relationships (SAR) of triterpenoids and their metabolic pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for creating specialized derivatives with targeted biological activities.

Basic Information

Product Name	(20R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One
CAS No.	19865-90-8
Molecular Formula	C30H50O3
Molecular Weight	458.72 g/mol
Synonyms	20(R),24-Epoxy-25-hydroxydammaran-3-one; 20(R)-25-Hydroxy-20,24-epoxydammaran-3-one; 20(R)-Dammar-20,24-epoxy-3-one, 25-hydroxy-; 20(R)-20,24-Epoxy-25-hydroxydammarane-3-one; 25-Hydroxy-20(R),24-epoxydammaran-3-one; Ginsenoside precursor intermediate; Dammarane triterpenoid epoxy ketone
EINECS	Contact for details

Quality Control

Our (20R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or pharmacopeial requirements (e.g., USP reference standard guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.