Description

(24R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One is a high-purity, specific stereoisomer of a dammarane-type triterpenoid, valued for its role as a critical intermediate and reference standard in advanced organic synthesis. This compound matters for its structural complexity and defined stereochemistry, which are essential for research into bioactive natural products and pharmaceutical development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, nutraceutical, and fine chemical industries working on novel therapeutic agents or high-value botanical extracts.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the semi-synthesis of novel triterpenoid derivatives with potential biological activity.
• Reference Standard: Used as a high-purity analytical standard for quality control and quantification in the analysis of ginseng, notoginseng, and other botanicals containing dammarane saponins.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of triterpenoids and their interactions with biological targets.
• Natural Product Synthesis: A crucial precursor in the total synthesis or structural modification of complex natural products for drug discovery programs.
• Nutraceutical Development: Used in the development and standardization of high-end herbal supplements where specific, characterized actives are required.

Basic Information

Product Name	(24R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One
CAS No.	19865-86-2
Molecular Formula	C30H50O3
Molecular Weight	458.72 g/mol
Synonyms	(24R)-20,24-Epoxy-25-hydroxydammaran-3-one; 20(R),24(R)-Epoxy-25-hydroxy-dammaran-3-one; 25-Hydroxy-20,24-epoxydammaran-3-one; Dammar-20(24),25-epoxide-3-one, 25-hydroxy-; A key dammarane triterpenoid intermediate; 20,24-Epoxy-25-hydroxy-5α-dammaran-3-one (24R-isomer); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (24R)-20,24-Epoxy-25-Hydroxy-5α-Dammaran-3-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% (24R-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.