Description

2-Pyrazinecarbonyl Chloride is a versatile and highly reactive acid chloride derivative of pyrazinecarboxylic acid. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the pyrazinecarbonyl moiety into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity reagent for constructing complex heterocyclic structures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing pyrazine or amide functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that leverage the pyrazine ring system for biological activity.
• Peptide Mimetics & Linker Chemistry: Employed to create peptide analogs and as a coupling agent or linker in bioconjugation and prodrug development.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of polymers and advanced organic materials with specific electronic properties.
• Research & Development: A fundamental tool in medicinal chemistry and academic research for exploring new chemical entities and structure-activity relationships.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized heterocyclic dyes and pigments.

Basic Information

Product Name	2-Pyrazinecarbonyl Chloride
CAS No.	19847-10-0
Molecular Formula	C5H3ClN2O
Molecular Weight	142.54 g/mol
Synonyms	Pyrazine-2-carbonyl chloride; 2-Pyrazinecarboxylic acid chloride; Pyrazinoic acid chloride; 2-Carboxypyrazine chloride; Pyrazinecarbonyl chloride; Pyrazine-2-carbonylchloride; 2-Pyrazinylcarbonyl chloride
EINECS	243-357-7

Quality Control

Our 2-Pyrazinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.