Description

1-Adamantaneacetyl Chloride is a highly versatile and reactive chemical intermediate characterized by its unique adamantane cage structure. This compound is crucial for introducing the lipophilic and rigid adamantyl moiety into target molecules, significantly altering their physical and biological properties. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing adamantane-containing drugs, including antiviral agents (e.g., amantadine derivatives), neurological therapeutics, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of novel pesticides and fungicides where the adamantane group enhances stability and bioactivity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-performance polymers with enhanced thermal stability and mechanical properties.
• Ligand & Catalyst Development: Employed to functionalize ligands for catalysis or to create novel organometallic complexes.
• Dendrimer & Nanomaterial Construction: Acts as a core or branching unit in the synthesis of complex dendritic architectures and functional nanomaterials.
• Organic Synthesis & Research: A fundamental reagent for peptide coupling (as an acid chloride) and for introducing the 1-adamantylacetyl group in various organic transformations.

Basic Information

Product Name	1-Adamantaneacetyl Chloride
CAS No.	19835-38-2
Molecular Formula	C₁₂H₁₇ClO
Molecular Weight	212.72 g/mol
Synonyms	1-Adamantylacetyl Chloride; 1-Adamantaneacetic Acid Chloride; (Adamantan-1-yl)acetyl Chloride; 2-(1-Adamantyl)acetyl Chloride; 1-Adamantylacetic Acid Chloride; NSC 334365; Adamantane-1-acetyl Chloride
EINECS	243-360-9

Quality Control

Our 1-Adamantaneacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity (typically ≥97% by HPLC or GC), and impurity profiles. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and reactive acid chloride nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool (2-8°C), dry, and well-ventilated area. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.