Description

2-(6-Amino-2-Fluoro-Purin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is a high-purity fluorinated nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel antiviral and anticancer agents, particularly as a precursor for modified oligonucleotides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Serves as a precursor for chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Oligonucleotide Synthesis: A modified nucleoside for creating fluorinated antisense oligonucleotides and siRNA constructs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial API manufacturing.

Basic Information

Product Name	2-(6-Amino-2-Fluoro-Purin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol
CAS No.	19768-92-4
Molecular Formula	C10H12FN5O4
Molecular Weight	285.23 g/mol
Synonyms	2-Fluoro-2'-deoxyadenosine; 2'-Deoxy-2-fluoroadenosine; 2-Fluoro-2'-deoxyadenosine; 2-F-dA; 2-Fluorodeoxyadenosine; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-2-fluoroadenine; 2-Fluoroadenosine 2'-deoxy; 2-F-2'-dA
EINECS	Contact for details

Quality Control

Our 2-(6-Amino-2-Fluoro-Purin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.