Description

7-Ethylguanine is a modified purine nucleobase derivative, specifically an alkylated analog of guanine. This compound serves as a critical building block and reference standard in pharmaceutical research and development, particularly in the study of nucleic acid chemistry and mutagenesis. It is essential for researchers and manufacturers in the fields of oncology, antiviral drug discovery, and biochemical diagnostics who require high-purity, well-characterized nucleobase analogs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a reference standard and substrate in studies of DNA alkylation, repair mechanisms, and mutagenesis.
• Diagnostic Reagent Manufacturing: Employed in the synthesis of probes and components for molecular diagnostic kits.
• Academic & Institutional Research: Fundamental tool for investigating the biological effects of alkylated DNA bases and their role in cellular processes.
• Standards & Metrology: Serves as a certified reference material (CRM) for analytical method validation and quality control in laboratories.

Basic Information

Product Name	7-Ethylguanine
CAS No.	19530-88-2
Molecular Formula	C7H9N5O
Molecular Weight	179.18 g/mol
Synonyms	7-Ethyl-1H-purin-6-amine; 7-Ethyl-6-aminopurine; 2-Amino-7-ethyl-1,7-dihydro-6H-purin-6-one; 7-Ethylguanine; Guanine, 7-ethyl-; 6-Amino-7-ethylpurine; NSC 51045
EINECS	Contact for details

Quality Control

Our 7-Ethylguanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.