Description

17-α-Hydroxypregnenolone CAS NO 19454-90-1 is a key steroid intermediate with significant importance in organic synthesis. This compound is valued for its role as a versatile building block in the production of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is primarily needed by manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for research, development, and commercial synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of steroidal drugs, including corticosteroids and other therapeutic hormones.
• Biochemical Research: Used as a reference standard and starting material in metabolic pathway studies and steroidogenesis research.
• Fine Chemical Synthesis: Serves as a building block for creating specialized steroid derivatives and novel chemical entities.
• API Development: Employed in the research and development of new Active Pharmaceutical Ingredients (APIs) within regulated pharmaceutical manufacturing.

Basic Information

Product Name	17-α-Hydroxypregnenolone
CAS No.	19454-90-1
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	17α-Hydroxypregnenolone; 3β,17α-Dihydroxypregn-5-en-20-one; Pregnenolone, 17α-hydroxy-; 17α-Hydroxy-5-pregnen-3β-ol-20-one; 17α-OH-Pregnenolone; 17α-Hydroxydelta5-pregnenolone; 17α-Hydroxypregn-5-ene-3β,20-diol
EINECS	243-106-8

Quality Control

Our 17-α-Hydroxypregnenolone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, IR, and other relevant methods, to meet the stringent requirements of pharmaceutical-grade intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.