Description

11A-Hydroxy-16,17A-Epoxyprogesterone is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. This compound is valued for its specific structural modifications, which are essential for creating novel therapeutic agents targeting hormone-related pathways. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of corticosteroids and other specialized steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid drugs and other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new therapeutic compounds with improved efficacy and safety profiles.
• Process Chemistry: Employed in scaling up synthetic routes for the commercial production of steroid-based medicines.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies investigating steroid hormone metabolism, receptor binding, and enzymatic conversion pathways.

Basic Information

Product Name	11A-Hydroxy-16,17A-Epoxyprogesterone
CAS No.	19427-36-2
Molecular Formula	C21H28O4
Molecular Weight	344.45 g/mol
Synonyms	11α-Hydroxy-16α,17α-epoxyprogesterone; 11α-Hydroxy-16α,17α-oxidopregn-4-ene-3,20-dione; 16α,17α-Epoxy-11α-hydroxyprogesterone; 11α-Hydroxy-16α,17α-epoxypregn-4-ene-3,20-dione; Pregna-4-ene-3,20-dione, 16,17-epoxy-11-hydroxy-, (11α,16α)-; 11α-Hydroxy-16α,17α-epoxy-4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 11A-Hydroxy-16,17A-Epoxyprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.